Browsing by Author "Wehinger, Sergio"

Now showing items 1-4 of 4

    • Characterization by gender of frailty syndrome in elderly people according to frail trait scale and fried ... 
      Palomo, Iván; García, Francisco; Albala Brevis, Cecilia Hortensia; Wehinger, Sergio; Fuentes, Manuel; Alarcón, Marcelo; Arauna, Diego; Montecino, Héctor; Méndez, Diego; Sepúlveda, Magdalena; Fuica, Peggy; Fuentes, Eduardo (MDPI, 2022)
      Background: Frailty has emerged as one of the main geriatric syndromes to be prevented in order to improve quality of health and life in the elderly. In this sense, the characterization of this syndrome through reliable ...
    • Phosphorylation of caveolin-1 on tyrosine-14 induced by ROS enhances palmitate-induced death of beta-pancreatic ... 
      Wehinger, Sergio; Ortiz, Rina; Díaz, María Inés; Aguirre, Adam; Valenzuela, Manuel; Llanos Vidal, Paola; Mc Master, Christopher; Leyton Campos, Lisette; Quest, Andrew F. G. (Elsevier, 2015)
      A considerable body of evidence exists implicating high levels of free saturated fatty acids in beta pancreatic cell death, although the molecular mechanisms and the signaling pathways involved have not been clearly ...
    • Rational design, synthesis and evaluation of γ-CD-containing cross-linked polyvinyl alcohol hydrogel as a ... 
      Marican, Adolfo; Avila-Salas, Fabián; Valdés, Oscar; Wehinger, Sergio; Villaseñor, Jorge; Fuentealba, Natalia; Arenas-Salinas, Mauricio; Argandoña, Yerko; Carrasco-Sánchez, Verónica; Durán-Lara, Esteban F. (MDPI AG, 2018)
      © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This study describes the in-silico rational design, synthesis and evaluation of cross-linked polyvinyl alcohol hydrogels containing γ-cyclodextrin (γ-CDHSAs) as ...
    • Rational development of a novel hydrogel as a pH-sensitive controlled release system for nifedipine 
      Avila-Salas, Fabián; Rodriguez Nuñez, Yeray A.; Marican, Adolfo; Castro, Ricardo I.; Villaseñor, Jorge; Santos, Leonardo S.; Wehinger, Sergio; Durán-Lara, Esteban F. (MDPI AG, 2018)
      © 2018 by the authors. This work depicts the rational development (in-silico design, synthesis, characterization and in-vitro evaluation) of polyvinyl alcohol hydrogels (PVAH) cross-linked with maleic acid (MA) and linked ...